中国组织工程研究

中国组织工程研究 ›› 2014, Vol. 18 ›› Issue (46): 7482-7486.doi: 10.3969/j.issn.2095-4344.2014.46.021

• 组织构建综述 tissue construction review • 上一篇    下一篇

髁突吸收：病因表现及现代修复治疗对策

李振兴，陈传俊   

  1. 安徽医科大学第三附属医院/合肥市第一人民医院口腔颌面外科，安徽省合肥市 230061
  • 修回日期:2014-10-17 出版日期:2014-11-12 发布日期:2014-11-12
  • 通讯作者: 陈传俊，博士，主任医师，教授，安徽医科大学第三附属医院/合肥市第一人民医院口腔颌面外科, 安徽省合肥市 230061
  • 作者简介:李振兴，男，1990年生，安徽省合肥市人，汉族，安徽医科大学在读硕士，主要从事口腔颌面外科研究。
  • 基金资助:

    合肥市科技计划项目资助(合科【2013】183号-37)

Condylar resorption: etiology manifestations and modern restorative treatment

Li Zhen-xing, Chen Chuan-jun   

  1. Department of Oral and Maxillofacial Surgery, the 3rd Affiliated Hospital of Anhui Medical University, Hefei 230061, Anhui Province, China
  • Revised:2014-10-17 Online:2014-11-12 Published:2014-11-12
  • Contact: Chen Chuan-jun, M.D., Chief physician, Professor, Department of Oral and Maxillofacial Surgery, the 3rd Affiliated Hospital of Anhui Medical University, Hefei 230061, Anhui Province, China
  • About author:Li Zhen-xing, Studying for master’s degree, Department of Oral and Maxillofacial Surgery, the 3rd Affiliated Hospital of Anhui Medical University, Hefei 230061, Anhui Province, China
  • Supported by:

    the Scientific and Technological Plan of Hefei City, No. [2013]183-37

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摘要：

背景：颞下颌关节髁突吸收由于其病因复杂，不同病因所引发的髁突吸收的表现、症状、发展和转归各不相同，目前国内尚无全面详细介绍髁突吸收的文章。

目的：分析髁突吸收的病因及发病机制、临床表现和诊治现状，为髁突吸收的临床修复治疗及进一步研究提供理论依据。
方法：由第一作者检索1990年1月至2014年1月PubMed数据及中国知网数据库相关文献。英文检索词为 temporomandibular joint，condylar resorption，pathogenesis，diagnosis ，treatment；中文检索词为颞下颌关节，髁突吸收，病因，诊断，治疗。纳入与髁突吸收病因、临床表现、诊断和治疗相关的文献38篇进行分析。

结果与结论：髁突吸收分为继发性髁突吸收和原发性髁突吸收，继发性髁突吸收有明确的致病因素，包括髁突骨折、正颌手术、结缔组织和自身免疫性疾病和类风湿性关节炎等。原发性髁突吸收主要与血清雌二醇浓度降低有关。可通过影像学检查结合临床表现及病史诊断髁突吸收，其治疗措施主要包括药物治疗、夹板治疗、咬合重建、正颌外科、肋骨-软骨移植和全关节置换，同时配合正畸治疗。目前，髁突吸收的病因和发病机制复杂，尚未完全阐明，需要进一步的深入研究。



中国组织工程研究杂志出版内容重点：组织构建；骨细胞；软骨细胞；细胞培养；成纤维细胞；血管内皮细胞；骨质疏松；组织工程


全文链接：

关键词: 组织构建, 骨组织工程, 颞下颌关节, 髁突吸收, 病因, 诊疗

Abstract:

BACKGROUND: Due to complex etiology, manifestations, symptoms, development and outcomes, there is no article about the detailed introduction of condylar resorption in China.

OBJECTIVE: To analyze the etiology, pathogenesis, clinical manifestations, diagnosis and treatment of condylar resorption, thereby providing a theoretical basis for clinical treatment of condylar resorption.
METHODS: An online computer-based retrieval of PubMed database and CNKI database between January 1990 and January 2014 was performed by the first author. The keywords were “temporomandibular joint, condylar resorption, pathogenesis, diagnosis, treatment” in English and Chinese, respectively. Finally 38 literatures on the etiology, clinical presentation, diagnosis and treatment of condylar resorption were included.
RESULTS AND CONCLUSION: Condylar resorption was subdivided into secondary condylar resorption and primary condylar resorption. Secondary condylar resorption has clear risk factors, including condylar fractures, orthognathic surgery, connective tissue or autoimmune diseases and rheumatoid arthritis. Primary condylar resorption may be associated with lowered serum estradiol concentration. Condylar resorption can be diagnosed by imaging studies combined with clinical manifestations and disease history. Condylar resorption treatment measures mainly include medications, splint treatment, occlusal reconstruction, orthognathic surgery, rib-cartilage transplantation and total joint replacement surgery, in conjunction with orthodontic treatment. Currently, its complex etiology and pathogenesis has not been fully elucidated, and we need to conduct further studies.


中国组织工程研究杂志出版内容重点：组织构建；骨细胞；软骨细胞；细胞培养；成纤维细胞；血管内皮细胞；骨质疏松；组织工程


全文链接：

Key words:  jaw, mandibular condyle, alveolar bone loss

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